Update from Sri Lankan Twin Registry: establishment of a population-based twin register and ongoing project on common mental disorders, alcohol abuse and suicidal ideations.
نویسندگان
چکیده
The Sri Lankan Twin Registry began as a volunteer register in 1997. Previously, we have shown door-to-door surveys as the best option to build a population-based twin register of older, adult twins. Our aim was to build a population-based twin register in the Colombo district and use it for twin studies on common mental disorders. We aimed to identify a random sample of 4000 twins ascertained through the twin census. The Colombo district is divided into 13 divisional secretariat divisions (DSDs) and each division is further divided into Grama Niladari divisions administratively. Grama niladaris (GNs) are civil servants and visit each household in order to update the electoral register. GNs were used to do a census of twins while they updated the electoral register. The correlation between population density and twin rate among DSDs was .81, and between twin rate and the percentage of returned forms (from each DSD) was .74. We received 9648 forms notifying about twins and multiples. After removing the duplicates and information about twins who live in other districts, there were 17,406 multiples remaining. After incorporating twins and multiples from various other feasibility studies we now have 19,040 multiples with 8.46 twins per 1000 people in the Colombo district.
منابع مشابه
Update From Sri Lankan Twin Registry: Establishment of a Population-Based
Twin Research and Human Genetics Volume 9 Number 6 pp. 868–874 T Sri Lankan Twin Registry began as a volunteer register in 1997. Previously, we have shown doorto-door surveys as the best option to build a population-based twin register of older, adult twins. Our aim was to build a population-based twin register in the Colombo district and use it for twin studies on common mental disorders. We a...
متن کاملUpdate From Sri Lankan Twin Registry: Establishment of a Population-Based Twin
Twin Research and Human Genetics Volume 9 Number 6 pp. 868–874 T Sri Lankan Twin Registry began as a volunteer register in 1997. Previously, we have shown doorto-door surveys as the best option to build a population-based twin register of older, adult twins. Our aim was to build a population-based twin register in the Colombo district and use it for twin studies on common mental disorders. We a...
متن کاملColombo Twin and Singleton Study (CoTASS): A description of a population based twin study of mental disorders in Sri Lanka
BACKGROUND The Sri Lankan twin registry is one of the first to be established in a developing country, and its design has ensured sampling from a wide range of environmental conditions. It thus has great potential to examine environmental and genetic influences on diverse phenotypes, including psychiatric disorders, in the context of a diversity of environmental exposures, which may not have be...
متن کاملSri Lankan Twin Registry.
Sri Lanka is an island with genetic diversity between the five main population groups. Our twin registry is the first in the developing world. Initially, we established a volunteer cohort of 4600 twin pairs through a competition advertised in the media. In addition, we have volunteer cohorts, birth registration-based cohorts through hospitals, and community-based cohorts. There is also a nation...
متن کاملSex-specific genetic influences on the comorbidity of alcoholism and major depression in a population-based sample of US twins.
BACKGROUND Alcoholism and depression frequently co-occur, but the origins of this comorbidity remain uncertain. Most previous family, twin, and adoption studies of these disorders have used cases ascertained through treatment settings, who may differ from cases in epidemiological samples. We studied the importance of genetic influences on risk for lifetime comorbidity of major depression and al...
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ورودعنوان ژورنال:
- Twin research and human genetics : the official journal of the International Society for Twin Studies
دوره 9 6 شماره
صفحات -
تاریخ انتشار 2006